I discovered (new to me, that is) something recently that will really help me when I get the new iPhone. It also could have helped me over the past year with my current iPod. 
Basically, each data type in iTunes can be synced to one computer but it doesn’t need to be synced on the same computer as the other types. This means that I can sync my calendar, contacts and podcasts on one computer (my PowerBook), while syncing Movies, Music and TV shows on another (my mac mini). Now I don’t need to find a syncing solution to keep two computers in sync, and I don’t have to manually manage my iPod just to add something to it from my PowerBook.
[...] bad I’ll likely have an iPhone in a month, plus it’s less of an issue now that I can more easily get the episodes to my iPod (in higher quality [...]